产品货号：
Z32629
中文名称：
APEX1抗体
英文名称：
Anti-APEX1 Antibody (Clone#OTI1H9)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-APEX1 Antibody (Clone#OTI1H9) |
| 指标别名 | AP endonuclease 1;APE;APE1;APE1;APEX1;APEN;APEX;APEX nuclease;APEX1;APX;HAP1;Protein REF 1;REF1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,monkey,mouse,rat,dog |
| 应用范围 | WB,IHC |
| 基因名称 | APEX1 |
| 克隆号 | OTI1H9 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 1-242 of human APEX1 (NP_001632) produced in E.coli. |
| 实际分子量 | 35.4KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | APEX1,also called apurinic endonuclease(APE),is a DNA repair enzyme having apurinic/apyrimidinic(AP) endonuclease,3-prime,5-prime-exonuclease,DNA 3-prime repair diesterase,and DNA 3-prime-phosphatase activities.The human APEX1 gene consists of 5 exons spanning 2.64kb and exists as a single copy in the haploid genome.Using in situ hybridization,the APEX1 gene is mapped to 14q11.2-q12.The predicted APEX1 protein,which contained probable nuclear transport signals,was identified as a member of a family of DNA repair enzymes found in lower organisms.The abundance of the large form of APEX1 was increased in leiomyoma extracts relative to myometrial tissue extracts,and the large form was dominant in cell lines derived from leiomyosarcomas.The exonuclease activity of nuclear APEX1 can remove the anti-HIV nucleoside analogs AZT and D4T from the 3-prime terminus of a nick more efficiently than can cytosolic exonucleases. |
| Uniprot ID | P27695 |
| 基因名全称 | APEX nuclease(multifunctional DNA repair enzyme) 1 |
| 蛋白名全称 | DNA-(apurinic or apyrimidinic site) lyase |
| 推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:150 |
相关搜索：APEX1抗体，APEX1单抗，Anti-APEX1 Antibody (Clone#OTI1H9)